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[Last Modified: ]

April 2007
Answer to Case 202

This was a case of malaria caused by Plasmodium ovale.  Many of the images depicted a classic presentation of P. ovale morphology; diagnostic features included:

  • enlarged infected RBCs (1 1/4 to 1 1/2×).
  • the presence of Schϋffner's dots in the infected RBCs.
  • elongated and fimbriated RBCs.
  • the presence of multiple stages of Plasmodium, including:
    • compact trophozoites with sturdy cytoplasm (Figure D)
    • round to oval gametocytes that almost filled the RBCs (Figures A, C, and F)
    • immature schizonts (Figures B and E).  Immature schizonts are often not helpful for making a diagnosis because the merozoites are not fully developed and therefore cannot be counted.  The size of the RBC can still be taken into consideration.

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