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In developing schizonts of P. knowlesi, Sinton and
Mulligan's stippling may be observed. The nucleus continues to divide
until there are up to 16 (average 10) merozoites. As the schizont
matures, it fills the host RBC and the pigment collects into one or a few
masses. In the mature schizont, the merozoites may appear 'segmented' and
the pigment has collected into a single mass.
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A |
A:
Schizonts of P. knowlesi. Figs. 16-23:
Increasingly mature schizonts.
Illustrations from: Coatney GR, Collins WE, Warren M, Contacos PG. The Primate
Malarias. Bethesda: U.S. Department of Health, Education and Welfare; 1971.
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B |
C |
B, C: Mature
schizonts of P. knowlesi in a thin blood smear from a patient
that traveled to the Philippines. Note also a ring-form
trophozoite to the right of the schizont in Figure C. Images
courtesy of the Wadsworth Center, New York State Department of Health.
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| D |
E |
D: Developing schizont of
P. knowlesi in a thin blood smear from the same patient seen in
Figures B and C.
E: Mature schizont of P. knowlesi in a thin blood smear
from the same patient seen in Figures B-D.
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