In addition to microscopy and
molecular methods, there are methods for detecting malaria parasites on the basis of
antigens or enzymatic activities associated with the parasites.
These methods include, among others:
- detection of an antigen
(histidine rich protein-2, HRP-2) associated with malaria parasites (especially P.
falciparum and P. vivax)
- detection of a Plasmodium
associated lactate dehydrogenase (pLDH) either through its enzymatic activity or by
The detection of
HRP-2 and of pLDH forms the basis for diagnostic kits that have been, and
continue to be evaluated. Consensus information, when available, will be reviewed.