Monthly case studies [Last Modified: ]

July, 2003

Case 111:
A man was seen by his physician for an uncomfortable, sporadic twitch of his eyelids.  Several years earlier the man had been to Nigeria and had a worm extracted from the surface of his eye.  His physician requested that a blood sample be collected and smears made and stained with Giemsa.  The stained slides were forwarded to CDC for confirmatory diagnosis.  A few objects were observed, ranging in size from about 250 to 265 micrometers in length.  Figures A and B show two of the objects on the thick film seen at 200× and 400× respectively.  Figures C and D (depicting the anterior and posterior parts respectively) show one of the objects seen at 1000× magnification.  What is your diagnosis?  Based on what criteria?

Case 111 Image A Case 111 Image B
A B

Case 111 Image C
C

Case 111 Image D
D

Acknowledgement: This case was kindly provided by the Indiana University Hospital and the Indiana State Department of Health.

Click here for the answer to Case 111.

Case 112:
A 56-year-old man occasionally eats medium-rare cooked fish.  One evening the man felt something moving in his mouth and, after he extracted it, discovered that it was a worm.  He visited his doctor to submit the worm for identification and because of gastrointestinal symptoms.  An ova and parasites (O and P) stool exam was performed and the results were negative.  Figure A shows an image of the entire worm taken without the aid of a microscope.  The worm was cleared using lacto-phenol to allow visualization of internal morphologic structures.  Figures B and C (40× magnification) show the anterior and posterior ends of the worm respectively.  Arrows in Figures D and E indicate a key diagnostic structure observed in a cross-sectional sample.  What is your diagnosis?  Based on what criteria?

Case 112 Image A
A

Case 112 Image B Case 112 Image C
B C

Case 112 Image D Case 112 Image E
D E

Acknowledgement: This case was kindly provided by the Indiana State Department of Health.

Click here for the answer to Case 112.

Images presented in the monthly case studies are from specimens submitted for diagnosis or archiving.  On rare occasions, clinical histories given may be partly fictitious.

 

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